Università del Salento

D Iacopetta, R Lappano, AR Cappello, M Madeo, E De Francesco, A Santoro, R Curcio, L Capobianco, V Pezzi, M Maggiolini, V Dolce. “SLC37A1 gene expression is up-regulated by epidermal growth factor in breast cancer cells.” (2010) Breast Cancer Res Treat, 122, 755-764.
D Iacopetta, C Carrisi, G De Filippis, VM Calcagnile, AR Cappello, A Chimento, R Curcio, A Santoro, A Vozza, V Dolce, F Palmieri, L Capobianco. “The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster.” (2010) FEBS J, 277, 1172-1181.
GV Gnoni, AM Giudetti, E Mercuri, F Damiano, E Stanca, P Priore, L Siculella. “Reduced activity and expression of mitochondrial citrate carrier in streptozotocin-induced diabetic rats.” (2010) Endocrinology, 151, 1551-1559.
G Serviddio, F Bellanti, AM Giudetti, GV Gnoni, A Petrella, R Tamborra, AD Romano, T Rollo, G Vendemiale, E Altomare. “A silybin-phospholipid complex prevents mitochondrial dysfunction in a rodent model of nonalcoholic steatohepatitis.” (2010) J Pharmacol Exp Ther, 332, 922-932.
A Stendardi, R Focarelli, P Piomboni, D Palumberi, F Serafini, A Ferramosca, V Zara. Evaluation of mitochondrial respiratory efficiency during in vitro capacitation of human spermatozoa. (2011) Int J Androl, 34, 247-255.
V Zara, L Conte. The Rieske Iron-Sulfur protein: Import and assembly into the cytochrome bc(1) complex of yeast mitochondria. (2011) Bioinorg Chem Appl, 2011:363941.
A Ferramosca, L Conte, V Zara. A krill oil supplemented diet reduces the activities of the mitochondrial tricarboxylate carrier and of the cytosolic lipogenic enzymes in rats. (2012) J Anim Physiol Anim Nutr, 96, 295-306.
L Conte, BL Trumpower, V Zara. Bcs1p can rescue a large and productive cytochrome bc(1) complex assembly intermediate in the inner membrane of yeast mitochondria. (2011) Biochim Biophys Acta, 1813, 91-101.
D Iacopetta, M Madeo, G Tasco, C Carrisi, R Curcio, E Martello, R Casadio, L Capobianco, V Dolce. “A novel subfamily of mitochondrial dicarboxylate carriers from Drosophila melanogaster: biochemical and computational studies.” (2011) BBA-Bioenergetics, 1807, 251-261.
L Capobianco, D Iacopetta, C Carrisi, M Madeo, AR Cappello, V Dolce. “An effective strategy for cloning the mitochondrial citrate carrier: identification, characterization and tissue distribution in silver eel.” (2011) Advances in Bioscience and Biotechnology, 2, 157-162.
G Serviddio, F Bellanti, AM Giudetti, GV Gnoni, N Capitanio, R Tamborra, AD Romano, M Quinto, M Blonda, G Vendemiale, E Altomare. “Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration.” (2011) Free Radic Biol Med, 51, 2234-2242.
G Serviddio, AM Giudetti, F Bellanti, P Priore, T Rollo, R Tamborra, L Siculella, G Vendemiale, E Altomare, GV Gnoni. “Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet.” (2011) PLoS ONE, 6(9): e24084.
P Piomboni, R Focarelli, A Stendardi, A Ferramosca, V Zara. The role of mitochondria in energy production for human sperm motility. (2012) Int J Androl, 35, 109-124.
A Ferramosca, S Pinto Provenzano, L Coppola, V Zara. Mitochondrial respiratory efficiency is positively correlated with human sperm motility. (2012) Urology, 79, 809-814.
A Ferramosca, A Conte, L Burri, K Berge, F De Nuccio, AM Giudetti, V Zara. A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats. (2012) PLoS ONE, 7 (6): e38797.
AR Cappello, C Guido, A Santoro, M Santoro, L Capobianco, D Montanaro, A Madeo, S Andò, V Dolce, S Aquila. “The mitochondrial citrate carrier (CIC) is present and regulates insulin secretion by human male gamete.” (2012) Endocrinology, 153, 1743-1754.
AM Giudetti, R Cagnazzo. “Beneficial effects of n-3 PUFA on chronic airway inflammatory diseases.” (2012) Prostaglandins Other Lipid Mediat, 99:57-67.
A Ferramosca, V Zara. Biogenesis of mitochondrial carrier proteins: Molecular mechanisms of import into mitochondria. (2013) Biochim Biophys Acta, 1833, 494-502.
A Ferramosca, S Pinto Provenzano, L Coppola, DD Montagna, V Zara. Oxidative stress negatively affects human sperm mitochondrial respiration. (2013) Urology, 82, 78-83.
E De Franchis, A Ferramosca, V Zara, L Piper. Incidence of risk factors on the onset of gestational diabetes mellitus: an empirical research in southern Italy. (2013) International Journal of Measurement Technologies and Instrumentation Engineering, 2, 8-22.
P Lunetti, AR Cappello, RM Marsano, CL Pierri, C Carrisi, E Martello, C Caggese, V Dolce, L Capobianco. “Mitochondrial glutamate carriers from Drosophila melanogaster: biochemical, evolutionary and modeling studies.” (2013) BBA-Bioenergetics, 1827, 1245-1255.
E Stanca, G Serviddio, F Bellanti, G Vendemiale, L Siculella, AM Giudetti. “Down-regulation of LPCAT expression increases platelet-activating factor level in cirrhotic rat liver: potential antiinflammatory effect of silybin.” (2013) Biochim Biophys Acta, 1832, 2019-2026.
AM Giudetti, F Damiano, GV Gnoni, L Siculella. “Low level of hydrogen peroxide induces lipid synthesis in BRL-3A cells through a CAP-independent SREBP-1a activation.” (2013) Int J Biochem Cell Biol, 45, 1419-1426.
F Bellanti, AD Romano, AM Giudetti, T Rollo, M Blonda, R Tamborra, G Vendemiale, G Serviddio. “Many faces of mitochondrial uncoupling during age: damage or defense?” (2013) J Gerontol A Biol Sci Med Sci, 68, 892-902.
T Cui, A Conte, JL Fox, V Zara, DR Winge. “Modulation of the respiratory supercomplexes in yeast: Enhanced formation of cytochrome oxidase increases the stability and abundance of respiratory supercomplexes”. (2014) J Biol Chem, 289, 6133-6141.
A Ferramosca, V Zara. Modulation of hepatic steatosis by dietary fatty acids. (2014) World Journal of Gastroenterology, 20, 1746-1755.
A Ferramosca, V Zara. Bioenergetics of mammalian sperm capacitation. (2014) Biomed Research International, 2014:902953.
A Ferramosca, V Zara. Dietary fat and hepatic lipogenesis: the mitochondrial citrate carrier as a sensor of metabolic changes. (2014) Advances in Nutrition, 5, 217-225.
A Ferramosca, A Conte, F Damiano, L Siculella, V Zara. Differential effects of high carbohydrate and high fat diets on hepatic lipogenesis in rats. (2014) European Journal of Nutrition, 53, 1103-1114.
S Felline, E Mollo, A Ferramosca, V Zara, F Regoli, S Gorbi, A Terlizzi. Can a marine pest reduce the nutritional value of Mediterranean fish flesh? (2014) Marine Biology, 161, 1275-1283.
C Carrisi, D Antonucci, P Lunetti, D Migoni, CR Girelli, V Dolce, FP Fanizzi, M Benedetti, L Capobianco. “Transport of Platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1).” (2014) J Bioinorg Biochem, 130, 28-31.
G Serviddio, F Bellanti, E Stanca, P Lunetti, M Blonda, R Tamborra, L Siculella, G Vendemiale, L Capobianco, AM Giudetti. “Silybin exerts antioxidant effects and induces mitochondrial biogenesis in liver of rat with secondary biliary cirrhosis.” (2014) Free Radic Biol Med, 73, 117-126.
V Dolce, AR Cappello, L Capobianco. Mitochondrial Tricarboxylate and Dicarboxylate-Tricarboxylate Carriers: from animals to Plants. (2014) IUBMB life, 66, 462- 471.
D Vergara, AM Giudetti, D Latorre, P Lunetti, P Simeone, D Lofrumento, F Denuccio, G Nicolardi, L Capobianco, M Maffia. “Molecular and biochemical alterations in epithelial to mesenchymal transition.” (2014) J Biotechnol.
A Ferramosca, A Conte, V Zara. “Krill oil ameliorates mitochondrial dysfunctions in rats treated with high-fat diet”. (2015) Biomed Res Int, 2015:645984.
A Conte, B Papa, A Ferramosca, V Zara. “The dimerization of the yeast cytochrome bc1 complex is an early event and is independent of Rip1”. (2015) Biochim Biophys Acta, 1853, 987-995.
L De Riccardis, A Rizzello, A Ferramosca, E Urso, F De Robertis, A Danieli, AM Giudetti, G Trianni, V Zara, M Maffia. “Bioenergetics profile of CD4+ T cells in relapsing remitting Multiple Sclerosis subjects.” (2015) J Biotechnol, 202: 31-39.
A Ferramosca, D Albani, L Coppola, V Zara. “Varicocele negatively affects sperm mitochondrial respiration.” (2015) Urology, 86, 735-739.
D Vergara, P Simeone, D Latorre, F Cascione, S Leporatti, M Trerotola, AM Giudetti, L Capobianco, P Lunetti, A Rizzello, R Rinaldi, S Alberti, M Maffia. “Proteomics analysis of E-Cadherin knockdown in epithelial breast cancer cells.” (2015) J Biotechnol, 202, 3-11.
D Vergara, M D'Alessandro, A Rizzello, L De Riccardis, P Lunetti, P Del Boccio, F De Robertis, G Trianni, M Maffia, AM Giudetti. “A lipidomic approach to the study of human CD4(+) T lymphocytes in multiple sclerosis.” (2015) BMC Neurosci, 24, 16:46.
A Aloisi, E Tarentini, A Ferramosca, V Zara, R Rinaldi. “Micro-oxygraph device for biosensoristic applications.” (2015) J Sensors, in press.
D Vergara, P Simeone, F Julien, M Trerotola, A Giudetti, L Capobianco, A Tinelli, C Bellomo, I Fournier, A Gaballo, S Alberti, M Salzet, M Maffia. “Translating epithelial mesenchymal transition markers into the clinic: novel insights from proteomics.” (2015) EuPA Open Proteomics, in press.
AM Giudetti, A Romano, AM Lavecchia, S Gaetani. “The role of brain cholesterol and its oxidized products in Alzheimer's disease.” (2015) Curr Alzheimer Res, in press.

LINEE DI RICERCA	RESPONSABILE	PAROLE CHIAVE	SSD
Effetto di differenti stati nutrizionali sulla biosintesi epatica degli acidi grassi e del colesterolo	Zara Ferramosca Giudetti	Lipogenesi Acidi grassi Colesterolo	BIO/10
Metabolismo energetico degli spermatozoi	Zara Ferramosca	Spermatozoi Bioenergetica Mitocondri	BIO/10
Studio del percorso di import di alcune proteine, in particolare i carrier di metaboliti, nei mitocondri isolati	Zara Ferramosca	Mitocondri Carrier Biogenesi	BIO/10
Identificazione, caratterizzazione funzionale e strutturale di proteine di trasporto della “famiglia MCF (Mitochondrial Carrier Family)”: proteine della membrana mitocondriale interna coinvolte nel traffico bidirezionale di metaboliti	Zara Capobianco Ferramosca Giudetti	Mitocondri Carrier Metaboliti	BIO/10
Studio del ruolo dei mitocondri nella tossicità di farmaci a base di Pt	Capobianco	Mitocondri Pt	BIO/10
Studio del metabolismo lipidico in differenti condizioni fisiologiche e patologiche (diabete, steatosi epatica, cirrosi biliare, cancro)	Zara Capobianco Ferramosca Giudetti	Metabolismo lipidico Diabete Steatosi Cirrosi Cancro	BIO/10
Studio del metabolismo energetico in differenti condizioni fisiologiche e patologiche (diabete, steatosi epatica, cirrosi biliare, cancro)	Zara Capobianco Ferramosca Giudetti	Mitocondri Diabete Steatosi Cirrosi Cancro	BIO/10
Studio della composizione lipidica di membrane cellulari in differenti condizioni fisiopatologiche	Giudetti	Lipidi Acigi grassi Lipidomica	BIO/10